Structure of PDB 3omx Chain B

Receptor sequence
>3omxB (length=190) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
KLAVAVVCSSNMNRSMEAHNFLAKKGFNVRSYGTGERVKLPGMAFDKPNV
YEFGTKYEDIYRDLESKDKEFYTQNGLLHMLDRNRRIKKCPERFQDTKEQ
FDIIVTVEERVYDLVVMHMESMESVDNRPVHVLNVDVVDNAEDALMGAFV
ITDMINMMAKSTDLDNDIDELIQEFEERRKRVILHSVLFY
3D structure
PDB3omx Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
ChainB
Resolution2.3366 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VO4 B C13 S14 S15 M17 N18 R19 D144 C8 S9 S10 M12 N13 R14 D139
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity
GO:0016791 phosphatase activity
GO:0017018 myosin phosphatase activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006369 termination of RNA polymerase II transcription
GO:0006397 mRNA processing
GO:0031124 mRNA 3'-end processing
Cellular Component
GO:0005634 nucleus
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3omx, PDBe:3omx, PDBj:3omx
PDBsum3omx
PubMed21204787
UniProtQ9VWE4

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