Structure of PDB 3oll Chain B

Receptor sequence
>3ollB (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
ALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMIS
WAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLV
LDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMY
PLVTATDSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSH
VRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAH
3D structure
PDB3oll Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain.
ChainB
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I310 K314 L324 E332 D489 E493 I49 K53 L63 E71 D225 E229
BS02 EST B E305 M336 F356 H475 L476 E44 M75 F95 H211 L212 BindingDB: IC50=1.1nM,Kd=0.5nM,EC50=2.1nM,Ki=0.015nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3oll, PDBe:3oll, PDBj:3oll
PDBsum3oll
PubMed20922740
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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