Structure of PDB 3og8 Chain B

Receptor sequence
>3og8B (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
MDKENKKLLCRKCKALACYTADVRVIEESHYTVLGDAFKECFVSRPHPKP
KQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATG
VQTLYSKWKDFHFEKIPFDPAEMSKLEH
3D structure
PDB3og8 Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B R811 K849 F853 R11 K49 F53
BS02 rna B H830 F853 K858 G874 I875 V886 K888 K907 W908 H30 F53 K58 G74 I75 V86 K88 K107 W108
BS03 ZN B C810 C813 C864 C869 C10 C13 C64 C69
External links
PDB RCSB:3og8, PDBe:3og8, PDBj:3og8
PDBsum3og8
PubMed20961956
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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