Structure of PDB 3odc Chain B

Receptor sequence
>3odcB (length=100) Species: 9606 (Homo sapiens) [Search protein sequence]
MKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGM
IDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVK
3D structure
PDB3odc Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.
ChainB
Resolution2.8 Å
3D
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Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B S120 R122 S123 R138 L151 S17 R19 S20 R35 L48
BS02 dna B R122 L151 R19 L48
BS03 ZN B C125 C128 H159 C162 C22 C25 H56 C59
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:3odc, PDBe:3odc, PDBj:3odc
PDBsum3odc
PubMed21233213
UniProtP09874|PARP1_HUMAN Poly [ADP-ribose] polymerase 1 (Gene Name=PARP1)

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