Structure of PDB 3ny1 Chain B

Receptor sequence
>3ny1B (length=70) Species: 9606 (Homo sapiens) [Search protein sequence]
LCGRVFKSGETTYSCRDCAIDPTCVLCMDCFQDSVHKNHRYKMHTSTGGG
FCDCGDTEAWKTGPFCVNHE
3D structure
PDB3ny1 Structural basis of substrate recognition and specificity in the N-end rule pathway.
ChainB
Resolution2.085 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C99 C124 C127 C149 C2 C27 C30 C52
BS02 ZN B C127 C151 C163 H166 C30 C54 C66 H69
BS03 ZN B C112 C115 H133 H136 C15 C18 H36 H39
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:3ny1, PDBe:3ny1, PDBj:3ny1
PDBsum3ny1
PubMed20835242
UniProtQ8IWV7|UBR1_HUMAN E3 ubiquitin-protein ligase UBR1 (Gene Name=UBR1)

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