Structure of PDB 3nxd Chain B

Receptor sequence
>3nxdB (length=258) Species: 10632 (JC polyomavirus) [Search protein sequence]
EVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNR
DMLPCYSVARIPLPNLNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNG
AGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVM
NTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNT
ATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQ
LRKRRVKN
3D structure
PDB3nxd Structure-function analysis of the human JC polyomavirus establishes the LSTc pentasaccharide as a functional receptor motif.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SIA B L54 K59 S60 N264 S266 S268 Q270 L30 K35 S36 N233 S235 S237 Q239
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

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Molecular Function

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Cellular Component
External links
PDB RCSB:3nxd, PDBe:3nxd, PDBj:3nxd
PDBsum3nxd
PubMed20951965
UniProtP03089|VP1_POVJC Major capsid protein VP1

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