Structure of PDB 3nkv Chain B

Receptor sequence
>3nkvB (length=169) Species: 9606 (Homo sapiens) [Search protein sequence]
EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELD
GKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWL
QEIDRYASNVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGIPFLETSAKN
ATNVEQAFMTMAAEIKKRM
3D structure
PDB3nkv The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b.
ChainB
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q67
Catalytic site (residue number reindexed from 1) Q64
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP B S17 G18 G20 K21 S22 C23 Y33 E35 T40 G66 N121 K122 D124 L125 S151 A152 K153 S14 G15 G17 K18 S19 C20 Y30 E32 T37 G63 N117 K118 D120 L121 S147 A148 K149
BS02 MG B S22 T40 S19 T37
BS03 AMP B F45 W62 Y77 F42 W59 Y74
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:3nkv, PDBe:3nkv, PDBj:3nkv
PDBsum3nkv
PubMed20651120
UniProtQ9H0U4|RAB1B_HUMAN Ras-related protein Rab-1B (Gene Name=RAB1B)

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