Structure of PDB 3nim Chain B

Receptor sequence
>3nimB (length=82) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
GSVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHV
CTDICTEFTSGICDCGDEEAWNSPLHCKAEEQ
3D structure
PDB3nim Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B K155 Q194 K43 Q82
BS02 ZN B C123 C148 C151 C175 C11 C36 C39 C63
BS03 ZN B H118 C151 C177 C189 H6 C39 C65 C77
BS04 ZN B C136 C139 H157 H160 C24 C27 H45 H48
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:3nim, PDBe:3nim, PDBj:3nim
PDBsum3nim
PubMed20835240
UniProtP19812|UBR1_YEAST E3 ubiquitin-protein ligase UBR1 (Gene Name=UBR1)

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