Structure of PDB 3n2e Chain B

Receptor sequence
>3n2eB (length=162) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence]
MQHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEE
LGEDNFRMFEKNLIDELKTLKTPHVISTGGGIVMHENLKGLGTTFYLKMD
FETLIKRLNQKERAKRPLLNNLTQAKELFEKRQALYEKNASFIIDARGGL
NNSLKQVLQFIA
3D structure
PDB3n2e Structures of Helicobacter pylori shikimate kinase reveal a selective inhibitor-induced-fit mechanism
ChainB
Resolution2.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.71: shikimate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OSA B F9 M10 R45 F48 E53 R57 G80 G81 M84 R116 R132 Y136 F9 M10 R45 F48 E53 R57 G80 G81 M84 R116 R132 Y136
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004765 shikimate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
GO:0016310 phosphorylation
GO:0019752 carboxylic acid metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3n2e, PDBe:3n2e, PDBj:3n2e
PDBsum3n2e
PubMed22438938
UniProtP56073|AROK_HELPY Shikimate kinase (Gene Name=aroK)

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