Structure of PDB 3mws Chain B

Receptor sequence
>3mwsB (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
PQITLWQRPVITVKIGKEVREALLDTGADDTVIEEIQLEGKWKPKMIGGI
GGFIKVRQYDNVTIDIQGRKAVGTVLVGPTPVNIIGRNFLTQIGATLNF
3D structure
PDB3mws Autocatalytic maturation, physical/chemical properties, and crystal structure of group N HIV-1 protease: relevance to drug resistance.
ChainB
Resolution1.09 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D125 T126 G127
Catalytic site (residue number reindexed from 1) D25 T26 G27
Enzyme Commision number 3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 017 B D125 G127 A128 D130 I147 G148 P181 I184 D25 G27 A28 D30 I47 G48 P81 I84
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3mws, PDBe:3mws, PDBj:3mws
PDBsum3mws
PubMed20737578
UniProtQ673V0

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