Structure of PDB 3ml4 Chain B

Receptor sequence
>3ml4B (length=207) Species: 10090 (Mus musculus) [Search protein sequence]
MTEAALVEGQVKLRKWKSRWLVLRKPSPVADCLLMLVYKDKCERSKGLRE
RSSLTLEDICGLEPALPYEGLAHTLAIICLSQAVMLGFDSHEAMCAWDTR
IRYALGEVHRFHVTVAPGTKLESGPATLHLCNDILVLARDIPPTVMGQWK
LSDLRRYGAVPNGFIFEGGTRCGYWAGVFFLSSAEGEQMSFLFDCIVRGI
SPTKGPF
3D structure
PDB3ml4 The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B E3 R27 P29 L39 E53 S56 E3 R24 P26 L36 E50 S53
BS02 peptide B D156 L157 R158 R159 Y160 G161 G172 T173 R174 D197 V200 R201 D153 L154 R155 R156 Y157 G158 G169 T170 R171 D194 V197 R198
Gene Ontology
Molecular Function
GO:0019901 protein kinase binding
Biological Process
GO:0061098 positive regulation of protein tyrosine kinase activity

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Molecular Function
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Biological Process
External links
PDB RCSB:3ml4, PDBe:3ml4, PDBj:3ml4
PDBsum3ml4
PubMed20603078
UniProtQ18PE0|DOK7_MOUSE Protein Dok-7 (Gene Name=Dok7)

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