Structure of PDB 3mbe Chain B

Receptor sequence
>3mbeB (length=178) Species: 10090 (Mus musculus) [Search protein sequence]
RHFVHQFKGECYFTNGTQRIRLVTRYIYNREEYLRFDSDVGEYRAVTELG
RHSAEYYNKQYLERTRAELDTACRHNYEETEVPTSLRRLEQPNVAISLSR
HNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVML
EMTPHQGEVYTCHVEHPSLKSPITVEWS
3D structure
PDB3mbe The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.
ChainB
Resolution2.886 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F11 G13 Y60 Y61 Y66 R70 E74 T77 H81 N82 E85 T86 E87 F7 G9 Y56 Y57 Y61 R64 E68 T71 H75 N76 E79 T80 E81
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3mbe, PDBe:3mbe, PDBj:3mbe
PDBsum3mbe
PubMed20407212
UniProtQ31135

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