Structure of PDB 3m6k Chain B

Receptor sequence

>3m6kB (length=357) Species: 190192 (Methanopyrus kandleri AV19) [Search protein sequence]

VYDAEFVGSEREFEEERETFLKGVKAYDGVLATRYLMDEELLELHQNFIL
LTGSYACSIDPTEDRYQNVIVRGVNFDERVQRLSTGGSPARYAIVYRRGW
RAIAKALDIDEEDVPAIEVRAVKRNPLQPALYRILVRYGRVDLMPVTVDE
VPPEMAGEFERLIERYDVPIDEKEERILEILRENPWTPHDEIARRLGLSV
SEVEGEKDPESSGIYSLWSRVVVNIEYDERTAKRHVKRRDRLLEELYEHL
EELSPLTRRWIVEHKRDIMRRYLEQRIVECALKLQDRYGIREDVALCLAR
AFDGSISMIATTPYRTLKDVCPDLTLEEAKSVNRTLATLIDEHGLSPDAA
DELIEHF

3D structure

PDB

3m6k Structures of minimal catalytic fragments of topoisomerase v reveals conformational changes relevant for DNA binding.

Chain

Resolution

2.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	PO4	B	C314 C338 P339 D340	C297 C321 P322 D323
BS02	PO4	B	R108 R131 R293 S322 S324	R97 R120 R276 S305 S307
BS03	PO4	B	R131 E215 Y226	R120 E204 Y215

External links

PDB	RCSB:3m6k, PDBe:3m6k, PDBj:3m6k
PDBsum	3m6k
PubMed	20637419
UniProt	Q977W1

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