Structure of PDB 3m3q Chain B

Receptor sequence
>3m3qB (length=159) [Search protein sequence]
MQGVNIYNISAGTSVDLAAPVTTGDIVTFFSSALNLNAGAGNPNNTTLNL
FAENGAYLLHIAFRLQENVIIFNSRQPDGPWLVEQRVSDVANQFAGIDGK
AMVTVFDHGDKYQVVINEKTVIQYTKQISGLTSSLSYNATEETSIFSTVV
EAVTYTGLA
3D structure
PDB3m3q Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL B N43 H59 R63 W80 E83 N44 H60 R64 W81 E84
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0004536 DNA nuclease activity
GO:0030246 carbohydrate binding
GO:0030247 polysaccharide binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006915 apoptotic process
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3m3q, PDBe:3m3q, PDBj:3m3q
PDBsum3m3q
PubMed20530247
UniProtQ6WY08|ATLE_CYCAE Anti-tumor lectin (Fragment)

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