Structure of PDB 3lmk Chain B

Receptor sequence
>3lmkB (length=439) Species: 9606 (Homo sapiens) [Search protein sequence]
RVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHT
LERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDKPIVGVIGPG
SSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQAR
AMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGISIAHSYKIYS
NAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFL
LLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNH
RNPWFQEFWQHRFQCRLEGKYNKTCNSSLTLKTHHVQDSKMGFVINAIYS
MAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILF
DENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMD
3D structure
PDB3lmk Metabotropic Glutamate receptor mGluR5 complexed with glutamate
ChainB
Resolution2.44 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B I79 N80 L85 L86 I54 N55 L60 L61
BS02 GLU B Y64 S151 S152 S173 A174 T175 Y223 D305 G306 K396 Y39 S101 S102 S123 A124 T125 Y173 D255 G256 K340
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3lmk, PDBe:3lmk, PDBj:3lmk
PDBsum3lmk
PubMed
UniProtP41594|GRM5_HUMAN Metabotropic glutamate receptor 5 (Gene Name=GRM5)

[Back to BioLiP]