Structure of PDB 3llm Chain B

Receptor sequence
>3llmB (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
VVPWSPPQSNWNPWTSSNIDEGPLAFATPEQISMDLKNELMYQLEQDHDL
QAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDD
FIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESI
LPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLR
DVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEV
3D structure
PDB3llm Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN B T418 E512 T90 E184
BS02 ADP B G414 G416 K417 T418 T419 R456 G86 G88 K89 T90 T91 R128
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding
GO:0033679 3'-5' DNA/RNA helicase activity

View graph for
Molecular Function
External links
PDB RCSB:3llm, PDBe:3llm, PDBj:3llm
PDBsum3llm
PubMed20510246
UniProtQ08211|DHX9_HUMAN ATP-dependent RNA helicase A (Gene Name=DHX9)

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