Structure of PDB 3l2w Chain B

Receptor sequence
>3l2wB (length=163) Species: 11963 (Human spumaretrovirus) [Search protein sequence]
DRPQKPFDKFFIDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPTKAPSTSA
TVKSLNVLTSIAIPKVIHSDQGAAFTSSTFAEWAKERGIHLEFSTPYHPQ
SSGKVERKNSDIKRLLTKLLVGRPTKWYDLLPVVQLALNNTYSPVLKYTP
HQLLFGIDSNTPF
3D structure
PDB3l2w Retroviral intasome assembly and inhibition of DNA strand transfer
ChainB
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN B D128 D185 D13 D70
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3l2w, PDBe:3l2w, PDBj:3l2w
PDBsum3l2w
PubMed20118915
UniProtP14350|POL_FOAMV Pro-Pol polyprotein (Gene Name=pol)

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