Structure of PDB 3kyb Chain B

Receptor sequence

>3kybB (length=381) Species: 573 (Klebsiella pneumoniae)

KSKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARDSETN
VMVHVYGPHIFHTDNETVWNYINKHAEMMPYVNRVKATVNGQVFSLPINL
HTINQFFSKTCSPDEARALIAEKGDSTIADPQTFEEQALRFIGKELYEAF
FKGYTIKQWGMQPSELPASILKRLPVRFNYDDNYFNHKFQGMPKCGYTQM
IKSILNHENIKVDLQREFIVDERTHYDHVFYSGPLDAFYGYQYGRLGYRT
LDFKKFIYQGDYQGCAVMNYCSVDVPYTRITEHKYFSPWEQHDGSVCYKE
YSRACEENDIPYYPIRQMGEMALLEKYLSLAENETNITFVGRLGTYRYLD
MDVTIAEALKTAEVYLNSLTDNQPMPVFTVS

3D structure

• PDB: 3kyb Structure of UDP-galactopyranose mutase bound to flavin mononucleotide
• Chain: B
• Resolution: 2.3 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): R174 R178 R250 R280 E301 Y349 D351
• Catalytic site (residue number reindexed from 1): R173 R177 R249 R279 E300 Y348 D350
• Enzyme Commision number: 5.4.99.9: UDP-galactopyranose mutase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	B	V9 G10 G12 S14 D33 Q34 R35 G40 N41 H60 I61 F219 G234 P235 Y313 Y314 R343 Y349 L350 D351 M352 T355	V8 G9 G11 S13 D32 Q33 R34 G39 N40 H59 I60 F218 G233 P234 Y312 Y313 R342 Y348 L349 D350 M351 T354
BS02	FMN	B	Q159 W160 Y185	Q158 W159 Y184
BS03	FMN	B	Q159 W160 Y185 Y314 Y349	Q158 W159 Y184 Y313 Y348
BS04	FMN	B	F151 F152 I171 R178	F150 F151 I170 R177

Gene Ontology

Molecular Function

• GO:0008767 UDP-galactopyranose mutase activity

External links

• PDB: RCSB:3kyb, PDBe:3kyb, PDBj:3kyb
• PDBsum: 3kyb
• UniProt: Q48485|GLF1_KLEPN UDP-galactopyranose mutase (Gene Name=rfbD)