Structure of PDB 3kuk Chain B

Receptor sequence
>3kukB (length=293) Species: 9913 (Bos taurus) [Search protein sequence]
HNDLVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKFVCVGGSPSR
MKAFIKYVAMELGFAHADYPNICEGTDRYAMFKVGPVLSVSHGMGVPSIA
IMLHELIKLLYHAHCSGVTLIRIGTSGGIGLEPGSVVITRQAVDPCFKPE
FEQIVLGKREVRNTDLDEQLVQELARCSAELGEFPTVVGNTMCTLDFYEG
QGRLDGALCSYTEKDKQDYLRAAYAAGIRNIEMEASVFAAMCNACGLRAA
VVCVTLLNRLEGDQISSPHDVLAEYQQRPQRLVGQFIKKRLMQ
3D structure
PDB3kuk Glycal formation in crystals of uridine phosphorylase.
ChainB
Resolution2.783 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E120 R274
Catalytic site (residue number reindexed from 1) E105 R259
Enzyme Commision number 2.4.2.3: uridine phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 B G59 R63 R137 T140 G46 R50 R122 T125
BS02 DUR B M109 T140 S141 G142 F212 Q216 R218 I246 E247 M248 M94 T125 S126 G127 F197 Q201 R203 I231 E232 M233
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004850 uridine phosphorylase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0047847 deoxyuridine phosphorylase activity
Biological Process
GO:0009116 nucleoside metabolic process
GO:0009164 nucleoside catabolic process
GO:0009166 nucleotide catabolic process
GO:0044206 UMP salvage
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3kuk, PDBe:3kuk, PDBj:3kuk
PDBsum3kuk
PubMed20364833
UniProtA5PJH9

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