Structure of PDB 3kmp Chain B

Receptor sequence
>3kmpB (length=123) Species: 10090 (Mus musculus) [Search protein sequence]
TSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG
QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECC
EFPFGSKQKEVCINPYHYKRVES
3D structure
PDB3kmp Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R74 H101 R65 H92 PDBbind-CN: Kd=111.9nM
BS02 dna B L71 L75 Q76 K81 L62 L66 Q67 K72 PDBbind-CN: Kd=111.9nM
BS03 ZN B C64 C109 C121 H126 C55 C100 C112 H117
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005667 transcription regulator complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3kmp, PDBe:3kmp, PDBj:3kmp
PDBsum3kmp
PubMed20147459
UniProtP70340|SMAD1_MOUSE Mothers against decapentaplegic homolog 1 (Gene Name=Smad1)

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