Structure of PDB 3kgd Chain B

Receptor sequence
>3kgdB (length=342) Species: 511145 (Escherichia coli str. K-12 substr. MG1655) [Search protein sequence]
HHHHHKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPG
LLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAG
SCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKI
GIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVL
LAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENIT
ERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAG
AGEFTVAHPSCHLLTNIAVVERFLPVRFSLIETDGVTRVSIE
3D structure
PDB3kgd Structure of the RNA 3'-phosphate cyclase-adenylate intermediate illuminates nucleotide specificity and covalent nucleotidyl transfer.
ChainB
Resolution1.68 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E14 H309
Catalytic site (residue number reindexed from 1) E17 H312
Enzyme Commision number 6.5.1.4: RNA 3'-terminal-phosphate cyclase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B S129 A130 P131 F135 F251 Y284 D287 Q288 H309 S132 A133 P134 F138 F254 Y287 D290 Q291 H312
BS02 SO4 B E14 R43 E17 R46
BS03 SO4 B R208 A260 R211 A263
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003963 RNA-3'-phosphate cyclase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006396 RNA processing
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3kgd, PDBe:3kgd, PDBj:3kgd
PDBsum3kgd
PubMed20399182
UniProtP46849|RTCA_ECOLI RNA 3'-terminal phosphate cyclase (Gene Name=rtcA)

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