Structure of PDB 3k5e Chain B

Receptor sequence
>3k5eB (length=324) Species: 9606 (Homo sapiens) [Search protein sequence]
NIQVVVRCRPFNLAERKSAHSIVECDPVRKEVSVRTGGDKSSRKTYTFDM
VFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERS
PNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFD
LLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAK
RTTAATLMNAYSSRSHSVFSVTIHMKETTEELVKIGKLNLVDLAGSENNI
NQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISP
ASLNLEETLSTLEYAHRAKNILNK
3D structure
PDB3k5e The structure of human kinesin-like motor protein Kif11/KSP/Eg5 in complex with ADP and enastrol.
ChainB
Resolution1.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.4: Transferred entry: 5.6.1.3.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 K5E B E116 E118 R119 W127 D130 A133 I136 P137 Y211 L214 E96 E98 R99 W107 D110 A113 I116 P117 Y191 L194
BS02 ADP B R24 P27 T107 G108 G110 K111 T112 F113 E118 R7 P10 T87 G88 G90 K91 T92 F93 E98
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function

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Biological Process
External links
PDB RCSB:3k5e, PDBe:3k5e, PDBj:3k5e
PDBsum3k5e
PubMed
UniProtP52732|KIF11_HUMAN Kinesin-like protein KIF11 (Gene Name=KIF11)

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