Structure of PDB 3jzq Chain B

Receptor sequence
>3jzqB (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMV
YCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLAT
3D structure
PDB3jzq Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B K50 M53 G57 I60 Y66 Q71 H72 V92 K93 P95 Y99 K26 M29 G33 I36 Y42 Q47 H48 V68 K69 P71 Y75
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3jzq, PDBe:3jzq, PDBj:3jzq
PDBsum3jzq
PubMed19910468
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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