Structure of PDB 3jcm Chain B

Receptor sequence
>3jcmB (length=429) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
NESTADILKQLPHERLQAVLEKIPEEDLEVRRLLSILKKPEVVENEDVQQ
RRIRLAEILMVDEIDLENINNDFFTPATSELIFARRFLINYSLERSRKRL
QKEMERHQKFNTRQELLSRRTELQRMANLELAGSQLVSTKPISAVSLSTD
DMVVATGSWAGDLQVLNSQTLQPLTQKLDSHVGKIGAIDWHPDSNNQMIS
CAEDGLIKNFQYSNEEGGLRLLGDLVGHERRISDVKYHPSGKFIGSASHD
MTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSMLWDI
RSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQL
NQILAHRNIVTQVRFSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAGH
TDKIISLDISNNSHFLVSGGWDRSIKLWN
3D structure
PDB3jcm The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis
ChainB
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B N66 E67 N45 E46
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0017070 U6 snRNA binding
GO:0030621 U4 snRNA binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000393 spliceosomal conformational changes to generate catalytic conformation
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0034247 snoRNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005687 U4 snRNP
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3jcm, PDBe:3jcm, PDBj:3jcm
PDBsum3jcm
PubMed26743623
UniProtP20053|PRP4_YEAST U4/U6 small nuclear ribonucleoprotein PRP4 (Gene Name=PRP4)

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