Structure of PDB 3ir2 Chain B

Receptor sequence
>3ir2B (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
HSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVKLNQRRGFLAN
QAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQE
MAKFISKNKHVSLCIKTARIYDDQGRAQEGLRTLAEAGAKISIMTYSEFK
HCWDTFVDHQGAPFQPWDGLDEHSQDLSGRLRAILQN
3D structure
PDB3ir2 Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces.
ChainB
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.38: single-stranded DNA cytosine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H257 C288 C291 H63 C94 C97
BS02 ZN B H248 H250 H54 H56
BS03 MG B S336 I337 S142 I143
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:3ir2, PDBe:3ir2, PDBj:3ir2
PDBsum3ir2
PubMed20152150
UniProtQ9HC16|ABC3G_HUMAN DNA dC->dU-editing enzyme APOBEC-3G (Gene Name=APOBEC3G)

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