Structure of PDB 3imj Chain B

Receptor sequence
>3imjB (length=100) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDV
QHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVP
3D structure
PDB3imj Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
ChainB
Resolution2.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AYI B R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121 R12 R31 S33 S35 S41 Q51 H52 F53 K54 L65 W66 MOAD: Ka=2100000M^-1
External links
PDB RCSB:3imj, PDBe:3imj, PDBj:3imj
PDBsum3imj
PubMed19886660
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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