Structure of PDB 3ikt Chain B

Receptor sequence
>3iktB (length=206) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
MKVPEAAISRLITYLRILEELEAQGVHRTSSEQLGELAQVTAFQVRKDLS
YFGSYGTRGVGYTVPVLKRELRHILGLNRKWGLCIVGMGRLGSALADYPG
FGESFELRGFFDVDPEKVGRPVRGGVIEHVDLLPQRVPGRIEIALLTVPR
EAAQKAADLLVAAGIKGILNFAPVVLEVPKEVAVENVDFLAGLTRLSFAI
LNPKWR
3D structure
PDB3ikt Structural basis for NADH/NAD+ redox sensing by a Rex family repressor.
ChainB
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B P4 R10 F43 Q44 R58 P4 R10 F43 Q44 R58
BS02 dna B S30 S31 R46 K47 S54 G56 G59 V60 G61 Y62 S30 S31 R46 K47 S54 G56 G59 V60 G61 Y62
BS03 NAD B A94 L95 Y98 A94 L95 Y98
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0051775 response to redox state
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3ikt, PDBe:3ikt, PDBj:3ikt
PDBsum3ikt
PubMed20513431
UniProtQ72I39|REX_THET2 Redox-sensing transcriptional repressor Rex (Gene Name=rex)

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