Structure of PDB 3ikc Chain B

Receptor sequence

>3ikcB (length=221) Species: 10090 (Mus musculus) [Search protein sequence]

EVMLVESGGGLVQPGNSLRLSCATSGFTFTDYYMSWVRQPPGKALEWLGF
IRNKAKGYTTEYSASVKGRFTISRDNSQSILYLQMNTLRAEDSATYYCAR
DISPSYGVYYEGFAYWGQGTLVTVSAATTTAPSVYPLVPGGSSVTLGCLV
KGYFPEPVTVKWNYGALSSGVRTVSSVLQSGFYSLSSLVTVPSSTWPSQT
VICNVAHPASKTELIKRIEPR

3D structure

PDB

3ikc The role of CDR H3 in antibody recognition of a synthetic analog of a lipopolysaccharide antigen.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	KME	B	K53 Y100C	K56 Y109	PDBbind-CN: -logKd/Ki=7.46,Kd=0.035uM
BS02	KDO	B	Y33 R52 I96 E100E	Y33 R52 I102 E111	PDBbind-CN: -logKd/Ki=7.46,Kd=0.035uM

External links

PDB	RCSB:3ikc, PDBe:3ikc, PDBj:3ikc
PDBsum	3ikc
PubMed	19767317

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