Structure of PDB 3ihl Chain B

Receptor sequence
>3ihlB (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTF
SPYEHGEVFVLNDGGEVQVVPHITDAVQEWVMNQAKVPVDGNKEEPQICV
IELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKT
KPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICI
HDVSSTYRVPVLLEEQSIVKYFKERLHLP
3D structure
PDB3ihl Human CTPS2 crystal structure
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.2: CTP synthase (glutamine hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B G13 I14 G15 K16 G17 I18 D246 V247 G13 I14 G15 K16 G17 I18 D202 V203
Gene Ontology
Molecular Function
GO:0003883 CTP synthase activity
Biological Process
GO:0006221 pyrimidine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3ihl, PDBe:3ihl, PDBj:3ihl
PDBsum3ihl
PubMed
UniProtQ9NRF8|PYRG2_HUMAN CTP synthase 2 (Gene Name=CTPS2)

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