Structure of PDB 3ibc Chain B

Receptor sequence
>3ibcB (length=92) Species: 9606 (Homo sapiens) [Search protein sequence]
KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQI
LTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
3D structure
PDB3ibc Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7.
ChainB
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y230 S231 W232 R233 P235 W240 S275 Q276 Y19 S20 W21 R22 P24 W29 S64 Q65
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3ibc, PDBe:3ibc, PDBj:3ibc
PDBsum3ibc
PubMed19655253
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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