Structure of PDB 3i59 Chain B

Receptor sequence
>3i59B (length=202) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
SHMDEILARAGIFQGVETKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKV
KIGRRAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMD
RDALRSWIADRPEISEQLLRVLARRLRRTNNNLADLDVPGRVAKQLLQLA
QRFGTLRVTHDLTQEEIAQLVGASRETVNKALADFAHRGWIRLEGKSVLI
SD
3D structure
PDB3i59 Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein.
ChainB
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 N6S B F38 L69 T70 F78 G79 E80 L81 S82 R89 T90 S91 T134 F33 L64 T65 F73 G74 E75 L76 S77 R84 T85 S86 T129
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0030552 cAMP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3i59, PDBe:3i59, PDBj:3i59
PDBsum3i59
PubMed19740754
UniProtP9WMH3|CRPL_MYCTU CRP-like cAMP-activated global transcriptional regulator (Gene Name=crp)

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