Structure of PDB 3i54 Chain B

Receptor sequence
>3i54B (length=219) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
NLYFQSHMDEILARAGIFQEPSAIAALLQPVDFPRGHTVFAEGEPGDRLY
IIISGKVKIGRRNLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSM
DRDALRSWIADRPEISEQLLRVLARRLRRTNNNLADLIFTDVPGRVAKQL
LQLAQRFGTQEGGALRVTHDLTQEEIAQLVGASRETVNKALADFAHRGWI
RLEGKSVLISDSERLARRA
3D structure
PDB3i54 Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP B F38 L69 T70 M72 F78 G79 E80 L81 S82 R89 T90 S91 R130 F40 L65 T66 M68 F74 G75 E76 L77 S78 R85 T86 S87 R126
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0030552 cAMP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Cellular Component
External links
PDB RCSB:3i54, PDBe:3i54, PDBj:3i54
PDBsum3i54
PubMed19740754
UniProtP9WMH3|CRPL_MYCTU CRP-like cAMP-activated global transcriptional regulator (Gene Name=crp)

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