Structure of PDB 3hjn Chain B

Receptor sequence
>3hjnB (length=184) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
MFITFEGIDGSGKSTQIQLLAQYLEKRGKKVILKREPGGTETGEKIRKIL
LEEEVTPKAELFLFLASRNLLVTEIKQYLSEGYAVLLDRYTDSSVAYQGF
GRNLGKEIVEELNDFATDGLIPDLTFYIDVDVETALKRNRFEKREFLERV
REGYLVLAREHPERIVVLDGKRSIEEIHRDVVRE
3D structure
PDB3hjn Crystal structure of thymidylate kinase in complex with dTDP and ADP from Thermotoga maritima
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.9: dTMP kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B G10 S11 G12 K13 S14 T15 R138 R176 S177 I178 G10 S11 G12 K13 S14 T15 R138 R172 S173 I174
BS02 TYD B D9 K13 E36 R47 F64 R68 R89 S93 S94 Y97 Q98 F145 D9 K13 E36 R47 F64 R68 R89 S93 S94 Y97 Q98 F141
Gene Ontology
Molecular Function
GO:0004798 thymidylate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0006227 dUDP biosynthetic process
GO:0006233 dTDP biosynthetic process
GO:0006235 dTTP biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0016310 phosphorylation
GO:0046940 nucleoside monophosphate phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3hjn, PDBe:3hjn, PDBj:3hjn
PDBsum3hjn
PubMed
UniProtQ9X0I3|KTHY_THEMA Thymidylate kinase (Gene Name=tmk)

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