Structure of PDB 3hjb Chain B

Receptor sequence

>3hjbB (length=551) Species: 666 (Vibrio cholerae)

AMLKNINPTQTQAWKALTAHFESAQDMDLKALFAQDSERFAKYSARFGQD
ILVDYSKNLVNAETMQHLFALAKETDLQSAITAMFKGEAINQTEDRAVLH
TALRNRSNSPVLVNGEDVMPAVNAVLAKMKAFSERVIGGEWKGFTGKAIT
DVVNIGIGGSDLGPYMVTEALVPYKNHLTVHFVSNVDGTHMAETLKNVDP
ETTLFLVASKTFTTQETMTNAHTARDWFLKAAGDEAHVAKHFAALSTNGK
AVAEFGIDTDNMFEFWDWVGGRYSLWSAIGLSIILSIGYDNFVELLAGAH
EMDQHFVNTPFESNIPVILALIGIWYNNFHGAESEAILPYDQYLHRFAAY
FQQGNMESNGKYVDRNGNPVTYQTGPIIWGEPGTNGQHAFYQLIHQGTKL
IPCDFIAPAVSHNLVGDHHQKLMSNFFAQTEALAFGKSAQAVQAELEKAG
KSAAEIAALVPFKVFEGNRPTNSILVKQITPRTLGNLIAMYEHKIFVQGV
IWNIFSFDQWGVELGKQLANQILPELADSAAVTSHDSSTNGLINAFKAFR
A

3D structure

• PDB: 3hjb 1.5 Angstrom Crystal Structure of Glucose-6-phosphate Isomerase from Vibrio cholerae.
• Chain: B
• Resolution: 1.5 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): K14 K209 E215 G270 R271 E356 H387 K515
• Catalytic site (residue number reindexed from 1): K15 K210 E216 G271 R272 E357 H388 K516
• Enzyme Commision number: 5.3.1.9: glucose-6-phosphate isomerase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	B	G330 E332	G331 E333

Gene Ontology

Molecular Function

• GO:0004347 glucose-6-phosphate isomerase activity
• GO:0016853 isomerase activity
• GO:0048029 monosaccharide binding
• GO:0097367 carbohydrate derivative binding

Biological Process

• GO:0006094 gluconeogenesis
• GO:0006096 glycolytic process
• GO:0051156 glucose 6-phosphate metabolic process
• GO:1901135 carbohydrate derivative metabolic process

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:3hjb, PDBe:3hjb, PDBj:3hjb
• PDBsum: 3hjb
• UniProt: Q9KUY4|G6PI_VIBCH Glucose-6-phosphate isomerase (Gene Name=pgi)