Structure of PDB 3h8v Chain B

Receptor sequence
>3h8vB (length=222) Species: 9606 (Homo sapiens) [Search protein sequence]
KIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDLSKVQAAEHTLRN
INPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCVDNFEA
RMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVAA
VCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMK
PNPQCDDRNCRKQQEEYKKKVA
3D structure
PDB3h8v Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C226 C229 C303 C308 C139 C142 C205 C210
Gene Ontology
Molecular Function
GO:0008641 ubiquitin-like modifier activating enzyme activity

View graph for
Molecular Function
External links
PDB RCSB:3h8v, PDBe:3h8v, PDBj:3h8v
PDBsum3h8v
PubMed20368332
UniProtQ9GZZ9|UBA5_HUMAN Ubiquitin-like modifier-activating enzyme 5 (Gene Name=UBA5)

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