Structure of PDB 3h78 Chain B

Receptor sequence
>3h78B (length=336) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
SENLYFQGNPILAGLGFSLPKRQVSNHDLVGRINTSDEFIVERTGVRTRY
HVEPEQAVSALMVPAARQAIEAAGLLPEDIDLLLVNTLSPDHHDPSQACL
IQPLLGLRHIPVLDIRAQASGLLYGLQMARGQILAGLARHVLVVCGEVLS
KRMDCSDRGRNLSILLGDGAGAVVVSAGESLEDGLLDLRLGADGNYFDLL
MTAAPGSASPTFLDENVLREGGGEFLMRGRPMFEHASQTLVRIAGEMLAA
HELTLDDIDHVICHQPNLRILDAVQEQLGIPQHKFAVTVDRLGNMASAST
PVTLAMFWPDIQPGQRVLVLTYGSGATWGAALYRKP
3D structure
PDB3h78 Structure of PqsD, a Pseudomonas quinolone signal biosynthetic enzyme, in complex with anthranilate.
ChainB
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.262: anthraniloyl-CoA anthraniloyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BE2 B A112 L193 F218 N287 A289 S317 A119 L200 F225 N294 A296 S324 PDBbind-CN: -logKd/Ki=4.24,Kd=57uM
BS02 BE2 B M220 M225 P259 I263 M227 M232 P266 I270 PDBbind-CN: -logKd/Ki=4.24,Kd=57uM
Gene Ontology
Molecular Function
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0044550 secondary metabolite biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3h78, PDBe:3h78, PDBj:3h78
PDBsum3h78
PubMed19694421
UniProtP20582|PQSD_PSEAE Anthraniloyl-CoA anthraniloyltransferase (Gene Name=pqsD)

[Back to BioLiP]