Structure of PDB 3h3t Chain B

Receptor sequence
>3h3tB (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
HRFVQKVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIV
LDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAII
IYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPL
NNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAP
ASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
3D structure
PDB3h3t Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 16H B R442 E446 H469 N504 V525 Y553 Y576 F579 R78 E82 H105 N140 V161 Y189 Y212 F215
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3h3t, PDBe:3h3t, PDBj:3h3t
PDBsum3h3t
PubMed20036255
UniProtQ9Y5P4|CERT_HUMAN Ceramide transfer protein (Gene Name=CERT1)

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