Structure of PDB 3h0g Chain B

Receptor sequence
>3h0gB (length=1150) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
ETLTQEDCWTVISSFFEETSLARQQLFSFDEFVQNTMQEIVDDDSTLTIN
FGQIYLSRPTMTEADGSTTTMFPQEARLRNLTYSSPLYVDMRKEDEEPSK
VFIGKIPIMLRSTFCILNGVSDSELYDLNECPYDQGGYFIINGSEKVIIA
QERSAANIVQVFKKAAPSPIAYVAEIRSALERGSRLISSMQIKLMARNTE
NSGQTIRATLPYIRSDIPIVIVFRALGVVPDRDILEHICYDPNDFQMLEM
MKPCIEEAFVIQDKDIALDYIGKRGSTTGVTREKRLRYAHDILQKELLPH
ITTMEGFETRKAFFLGYMIHRMLLCALERREPDDRDHFGKKRLDLAGPLL
ASLFRMLFRKMTRDVYKYMQKCVETNREFNLTLAVKSNIITNGLRYSLAT
GNWGDQKRSMVNRVGVSQVLNRYTFASTLSHLRRTNTPIGRDGKLAKPRQ
LHNTHWGMVCPAETPEGQACGLVKNLSLMSYVSVGSPSAPIIEFLEEWGL
ETLEDYNPSASPNATKVFVNGVWLGVHRDPAHLTETLRSLRRRLDISAEV
SIVRDIREKELRLFTDAGRICRPLFIVDNNPNSERRGELCIRKEHIQQLI
EDKDRYDIDPEQRFGWTALVSSGLIEYLDAEEEETVMIAMSPEDLEASRQ
MQAGYEVKEELDPAQRVKPAPNPHVHAWTHCEIHPAMILGILASIIPFPD
HNQSPRNTYQSAMGKQAMGVYLTNYQVRMDTMANILYYPQKPLATTRSME
YLKFRELPAGQNAIVAILCYSGYNQEDSIIMNQASIDRGLFRSIFYRTYT
DQEKKIGMTVMEEFERPVRSTTLRMKHGTYDKLEDDGLIAPGTRVSGEDI
IIGKTAPIQLHAKRDVSTPLRSTESGIVDQVMVTTNQEGLKFVKVRMRST
RIPQIGDKFASRHGQKGTIGMTYRHEDMPFSAQGIVPDIIINPHAIPSRM
TVAHLVECQLSKVSALSGFEGDATPFTDVTVEAVSKLLRSHGFQSRGFEV
MYHGHTGRKLVAQVFLGPTYYQRLKHLVDDKIHARARGPVQILTRQPVEG
RSRDGGLRFGEMERDCQISHGCSSVLRERLFDCSDAYRVIVCDICGLIAI
ASYKKDSYECRSCQNRTRFSQVYLPYAAKLLFQELMSMNIAPRLFTKNHK
3D structure
PDB3h0g Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.
ChainB
Resolution3.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C1152 C1173 C1092 C1113
Gene Ontology
Molecular Function
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0140727 siRNA-mediated pericentric heterochromatin formation
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005721 pericentric heterochromatin
GO:0005829 cytosol
GO:0016591 RNA polymerase II, holoenzyme

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3h0g, PDBe:3h0g, PDBj:3h0g
PDBsum3h0g
PubMed19458260
UniProtQ02061|RPB2_SCHPO DNA-directed RNA polymerase II subunit RPB2 (Gene Name=rpb2)

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