Structure of PDB 3gwz Chain B

Receptor sequence
>3gwzB (length=339) Species: 1914 (Streptomyces lavendulae) [Search protein sequence]
GTAARAAAEETVNDILQGAWKARAIHVAVELGVPELLQEGPRTATALAEA
TGAHEQTLRRLLRLLATVGVFDDLGHDDLFAQNALSAVLLPDPASPVATD
ARFQAAPWHWRAWEQLTHSVRTGEASFDVANGTSFWQLTHEDPKARELFN
RAMGSVSLTEAGQVAAAYDFSGAATAVDIGGGRGSLMAAVLDAFPGLRGT
LLERPPVAEEARELLTGRGLADRCEILPGDFFETIPDGADVYLIKHVLHD
WDDDDVVRILRRIATAMKPDSRLLVIDNLIDERPAASTLFVDLLLLVLVG
GAERSESEFAALLEKSGLRVERSLPCGAGPVRIVEIRRA
3D structure
PDB3gwz Structural characterization of the mitomycin 7-O-methyltransferase.
ChainB
Resolution1.91 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H259 D260 D287 E313
Catalytic site (residue number reindexed from 1) H249 D250 D277 E303
Enzyme Commision number 2.1.1.316: mitomycin 6-O-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B M163 S167 G190 G191 G192 E213 R214 D240 F241 K255 H256 M153 S157 G180 G181 G182 E203 R204 D230 F231 K245 H246
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
Biological Process
GO:0032259 methylation
GO:1901663 quinone biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3gwz, PDBe:3gwz, PDBj:3gwz
PDBsum3gwz
PubMed21538548
UniProtQ9X5T6|MMCR_STRLA Mitomycin biosynthesis 6-O-methyltransferase (Gene Name=mmcR)

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