Structure of PDB 3gqo Chain B

Receptor sequence
>3gqoB (length=159) Species: 36385 (Venezuelan equine encephalitis virus (strain P676)) [Search protein sequence]
APSYHVVRGDIATATEGVIINAANSKGQPGGGVCGALYKKFPESFDLQPI
EVGKARLVKGAAKHIIHAVGPNFNKVSEVEGDKQLAEAYESIAKIVNDNN
YKSVAIPLLSTGIFSGNKDRLTQSLNHLLTALDTTDADVAIYCRDKKWEM
TLKEAVARR
3D structure
PDB3gqo The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 APR B G9 D10 I11 A22 N24 G30 G31 G32 V33 C34 L108 S110 T111 G112 I113 F114 R144 G9 D10 I11 A22 N24 G30 G31 G32 V33 C34 L108 S110 T111 G112 I113 F114 R144
External links
PDB RCSB:3gqo, PDBe:3gqo, PDBj:3gqo
PDBsum3gqo
PubMed19386706
UniProtP36328|POLN_EEVVP Polyprotein P1234

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