Structure of PDB 3goy Chain B

Receptor sequence
>3goyB (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
KQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQA
KKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRAYGKGTYFAVNAN
YSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLY
DTVTDNVHHPSLFVAFYDYQAYPEYLITFRK
3D structure
PDB3goy Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3AB B Y1633 A1635 Y1640 Y1646 Y94 A96 Y101 Y107
Gene Ontology
Molecular Function
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:3goy, PDBe:3goy, PDBj:3goy
PDBsum3goy
PubMed22343925
UniProtQ460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 (Gene Name=PARP14)

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