Structure of PDB 3gey Chain B

Receptor sequence
>3geyB (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
LPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNA
FLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCSYG
KGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPP
KNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT
3D structure
PDB3gey Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P34 B H537 G538 Y569 Y576 S577 Y582 H78 G79 Y104 Y111 S112 Y117 BindingDB: IC50=8913nM
Gene Ontology
Molecular Function
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity

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Molecular Function
External links
PDB RCSB:3gey, PDBe:3gey, PDBj:3gey
PDBsum3gey
PubMed25635049
UniProtQ460N3|PAR15_HUMAN Protein mono-ADP-ribosyltransferase PARP15 (Gene Name=PARP15)

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