Structure of PDB 3gbu Chain B

Receptor sequence
>3gbuB (length=302) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
LIASIGELLIDLISVEEGDLKDVRLFEKHPGGAPANVAVGVSRLGVKSSL
ISKVGNDPFGEYLIEELSKENVDTRGIVKDEKKHTGIVFVQLKGASPSFL
LYDDVAYFNMTLNDINWDIVEEAKIVNFGSVILARNPSRETVMKVIKKIK
GSSLIAFDVNLRLDLWRGQEEEMIKVLEESIKLADIVKASEEEVLYLENQ
GVEVKGSMLTAITLGPKGFRLIKNETVVDVPSYNVNPLDTTGAGDAFMAA
LLVGILKLKGLDLLKLGKFANLVAALSTQKRGAWSTPRKDELLKYKEARE
VL
3D structure
PDB3gbu Crystal structure of an uncharacterized sugar kinase PH1459 from Pyrococcus horikoshii in complex with ATP
ChainB
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G244 A245 G246 D247
Catalytic site (residue number reindexed from 1) G242 A243 G244 D245
Enzyme Commision number 2.7.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B K190 T215 G217 P218 G220 S234 V237 A245 G246 A276 K188 T213 G215 P216 G218 S232 V235 A243 G244 A274
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008865 fructokinase activity
GO:0016301 kinase activity
Biological Process
GO:0006000 fructose metabolic process
GO:0016310 phosphorylation
GO:0046835 carbohydrate phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3gbu, PDBe:3gbu, PDBj:3gbu
PDBsum3gbu
PubMed
UniProtO59128|Y1459_PYRHO Putative sugar kinase PH1459 (Gene Name=PH1459)

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