Structure of PDB 3g9m Chain B

Receptor sequence
>3g9mB (length=78) Species: 10116 (Rattus norvegicus) [Search protein sequence]
HMCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKI
RRKNCPACRYRKCLQAGMNLEARKTKKK
3D structure
PDB3g9m DNA binding site sequence directs glucocorticoid receptor structure and activity.
ChainB
Resolution1.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B C450 H451 Y452 K461 K465 K490 C13 H14 Y15 K24 K28 K53 PDBbind-CN: Kd=0.15uM
BS02 dna B S459 R466 R489 K490 R496 S22 R29 R52 K53 R59 PDBbind-CN: Kd=0.15uM
BS03 ZN B C440 C443 C457 C460 C3 C6 C20 C23
BS04 ZN B C476 C482 C492 C495 C39 C45 C55 C58
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:3g9m, PDBe:3g9m, PDBj:3g9m
PDBsum3g9m
PubMed19372434
UniProtP06536|GCR_RAT Glucocorticoid receptor (Gene Name=Nr3c1)

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