Structure of PDB 3fr3 Chain B

Receptor sequence
>3fr3B (length=197) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
NIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKD
TPFEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGV
QDIHYKFNNTAANETTFLNEDLPKWSGYFEKLLKKNHTNNYYFVGNNLTY
ADLAVFNLYDDIETKYPSSLKNFPLLKAHNEFISNLPNIKNYITNRK
3D structure
PDB3fr3 Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118
ChainB
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y9 K15 R20
Catalytic site (residue number reindexed from 1) Y6 K12 R17
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDS B A115 T118 A112 T115
BS02 GDS B Y9 F10 A12 G14 Q58 V59 Q71 S72 Y6 F7 A9 G11 Q55 V56 Q68 S69
External links
PDB RCSB:3fr3, PDBe:3fr3, PDBj:3fr3
PDBsum3fr3
PubMed
UniProtQ8ILQ7|GST_PLAF7 Glutathione S-transferase (Gene Name=GST)

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