Structure of PDB 3fqd Chain B

Receptor sequence
>3fqdB (length=332) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
MLREFSFYDVPPAHVPPVSEPLEIACYSLSRDRELLLDDSKLSYYYPPPL
FSDLNTGFPNRFHPPKSDPDPISIVKDVLMTKGIQMNSSFLTWRGLITKI
MCAPLDPRNHWETYLVMDPTSGIIMMEERTRSETSYANQDRMCYWGYKFE
AISTLPEIWDACSRDQIEQRDNQDVVPDEQYCSIVKINIGKSKLILAGEV
DCIWDKKPCSENPNLHYVELKTSKKYPLENYGMRKKLLKYWAQSFLLGIG
RIIIGFRDDNGILIEMKELFTHQIPKMLRPYFKPNDWTPNRLLVVLEHAL
EWIKQTVKQHPPSTEFTLSYTGGSKLVLRQII
3D structure
PDB3fqd Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B E150 D201 E239 L240 E150 D201 E219 L220
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0004518 nuclease activity
GO:0005515 protein binding
GO:0019003 GDP binding
GO:0034353 mRNA 5'-diphosphatase activity
GO:0046872 metal ion binding
GO:0110152 RNA NAD+-cap (NAD+-forming) hydrolase activity
GO:0140432 5'-hydroxyl dinucleotide hydrolase activity
GO:1990174 phosphodiesterase decapping endonuclease activity
Biological Process
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0006397 mRNA processing
GO:0110155 NAD-cap decapping
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0090730 Las1 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3fqd, PDBe:3fqd, PDBj:3fqd
PDBsum3fqd
PubMed19194460
UniProtO13836|DXO_SCHPO Decapping nuclease din1 (Gene Name=din1)

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