Structure of PDB 3foe Chain B

Receptor sequence
>3foeB (length=433) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence]
QNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNT
FDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMHGN
NGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTV
LPAAFPNLLVNTDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFP
TIIQGRDEIKKAYETGKGRVVVRSEIEKLKGGKEQIVITEINKANLVKKI
DDVRVNNKVIELNTELVLNYLFKYTDLQINFNMVAIDNFTPRQVGIVPIL
SSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASE
NKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKI
AMLAAIIGDERTMYNLMKKELREVKKKFATPRL
3D structure
PDB3foe Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases
ChainB
Resolution4.001 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B V40 H74 H76 R87 V36 H70 H72 R83
BS02 NFX B G77 S79 G73 S75
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006265 DNA topological change
Cellular Component
GO:0005694 chromosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3foe, PDBe:3foe, PDBj:3foe
PDBsum3foe
PubMed19448616
UniProtP72525|PARC_STRPN DNA topoisomerase 4 subunit A (Gene Name=parC)

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