Structure of PDB 3fde Chain B

Receptor sequence
>3fdeB (length=206) Species: 10090 (Mus musculus) [Search protein sequence]
HMPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLV
LAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALN
CHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVV
KYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYL
EALANK
3D structure
PDB3fde UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
ChainB
Resolution1.41 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B F437 R438 V451 A452 G453 A468 G470 Y471 D474 Y483 T484 S486 R496 K544 F21 R22 V35 A36 G37 A52 G54 Y55 D58 Y67 T68 S70 R80 K128
BS02 dna B R448 H450 H455 R457 S458 N494 R496 N508 R32 H34 H39 R41 S42 N78 R80 N92
External links
PDB RCSB:3fde, PDBe:3fde, PDBj:3fde
PDBsum3fde
PubMed19077538
UniProtQ8VDF2|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)

[Back to BioLiP]