Structure of PDB 3f8d Chain B

Receptor sequence
>3f8dB (length=309) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
VKPGEKFDVIIVGLGPAAYGAALYSARYMLKTLVIGETPGGQLTEAGIVD
DYLGLIEIQASDMIKVFNKHIEKYEVPVLLDIVEKIENRDEFVVKTKRKG
EFKADSVILGIGVKRRKLGVPGEQEFAGRGISYCSVADAPLFKNRVVAVI
GGGDSALEGAEILSSYSTKVYLIHRRDTFKAQPIYVETVKKKPNVEFVLN
SVVKEIKGDKVVKQVVVENLKTGEIKELNVNGVFIEIGFDPPTDFAKSNG
IETDTNGYIKVDEWMRTSVPGVFAAGDCTSAWLGFRQVITAVAQGAVAAT
SAYRYVTEK
3D structure
PDB3f8d Structure and stability of a thioredoxin reductase from Sulfolobus solfataricus: a thermostable protein with two functions
ChainB
Resolution1.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C144 A147 D148
Catalytic site (residue number reindexed from 1) C134 A137 D138
Enzyme Commision number 1.6.99.3: Deleted entry.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G22 L23 G24 P25 A26 G45 E46 T47 G50 Q51 E54 A55 D60 I91 V92 G120 I121 G122 Y143 A147 G286 D287 R296 Q297 V298 G13 L14 G15 P16 A17 G36 E37 T38 G41 Q42 E45 A46 D51 I82 V83 G110 I111 G112 Y133 A137 G276 D277 R286 Q287 V288
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004791 thioredoxin-disulfide reductase (NADPH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0019430 removal of superoxide radicals
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3f8d, PDBe:3f8d, PDBj:3f8d
PDBsum3f8d
PubMed19110078
UniProtQ8X236

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