Structure of PDB 3f78 Chain B

Receptor sequence
>3f78B (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
GNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSY
KTEFDFSDYVKWKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGAR
PDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKF
ASKPASEFVKILDTFEKLKDLFTELQKKIY
3D structure
PDB3f78 Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems.
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ICF B I235 Y257 K287 E301 L302 K305 Y307 I108 Y130 K160 E174 L175 K178 Y180
External links
PDB RCSB:3f78, PDBe:3f78, PDBj:3f78
PDBsum3f78
PubMed19332643
UniProtP20701|ITAL_HUMAN Integrin alpha-L (Gene Name=ITGAL)

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